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Danazol

  • $1.49
  • Availability: In Stock
  • Active Ingredient Danazol
Danazol is indicated for the treatment of endometriosis amenable to hormonal management.
Other names of Danazol: a   b   c   d   e   f   g   h   i   j   k   l   m   n   o   p   q   r   s   t   u   v   w   x   y   z  
Azol   Anargil   Anargil   Azol  
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100 mg
Product name Per Pill Per Pack  
30 pills $3.65 $109.58
60 pills $3.00 $219.15 $180.10
90 pills $2.78 $328.73 $250.62
120 pills $2.68 $438.30 $321.14
180 pills $2.57 $657.45 $462.19
200 mg
Product name Per Pill Per Pack  
30 pills $4.50 $134.90
60 pills $3.42 $269.81 $205.06
90 pills $3.06 $404.71 $275.20
120 pills $2.88 $539.62 $345.36
180 pills $2.70 $809.42 $485.66
50 mg
Product name Per Pill Per Pack  
30 pills $2.06 $61.88
60 pills $1.72 $123.75 $102.96
90 pills $1.60 $185.63 $144.05
120 pills $1.54 $247.50 $185.14
180 pills $1.49 $371.25 $267.30

INDICATIONS

Danazol is used to treat a number of different medical problems. These include:

  • Endometriosis;
  • Fibrocystic breast disease (cysts in the breasts);
  • Hereditary angioedema (swelling of the different parts of the body, such as abdomen or stomach, arms, legs, throat, skin, or sexual organs. 

INSTRUCTIONS

It is very important that you use danazol only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects.

You must start taking danazol while you are having your monthly period.

In order for danazol to help you, it must be taken regularly for the full time of treatment as ordered by your doctor.

If you miss a dose of danazol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

DOSAGE

The dose of danazol will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of danazol. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
For oral dosage form (capsules):
For treatment of mild endometriosis:
Adults—At first, 200 to 400 milligrams (mg), divided in two doses, for at least 3 to 6 months and up to 9 months. Your doctor may adjust your dose as needed and tolerated.
Children—Use and dose must be determined by your doctor.
For treatment of moderate to severe endometriosis:
Adults—At first, 800 milligrams (mg) per day, divided in two doses, for at least 3 to 6 months and up to 9 months. Your doctor may adjust your dose as needed and tolerated.
Children—Use and dose must be determined by your doctor.
For treatment of fibrocystic breast disease:
Adults—100 to 400 milligrams (mg) per day, divided in two doses. Your doctor may adjust your dose as needed and tolerated.
Children—Use and dose must be determined by your doctor.
For prevention of hereditary angioedema:
Adults—At first, 200 milligrams (mg) two or three times a day. Your doctor may adjust your dose as needed and depending upon your condition.
Children—Use and dose must be determined by your doctor.

STORAGE

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.

SAFETY INFORMATION

It is very important that your doctor check your progress at regular visits to make sure that danazol does not cause unwanted effects. Blood tests may be needed to check for unwanted effects.

Using danazol while you are pregnant can harm your unborn baby. If you are a woman who can bear children, your doctor may give you a pregnancy test before you start using danazol to make sure you are not pregnant. Your birth control pills may not work as well while you are using danazol. You must use an effective form of birth control (e.g., a condom, a diaphragm, spermicide) to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.

Using danazol may cause irregular monthly periods or absence of menstrual period. If your regular monthly period does not begin within 60 to 90 days after you stop taking danazol, check with your doctor right away.

Check with your doctor right away if you are a female and have a larger clitoris (sexual organ), deepening of your voice, or unusual hair growth after taking danazol. Your doctor may advise you to stop taking the medicine so these side effects do not get worse.

Stop using danazol and check with your doctor if you have the following symptoms while taking danazol: blurred vision; change in the ability to see colors, especially blue or yellow; headache; nausea; or vomiting.

For patients with diabetes:
danazol may affect blood sugar levels. If you notice a change in the results of your blood or urine sugar tests, check with your doctor.

Before you have any medical tests, tell the medical doctor in charge that you are taking danazol. The results of some tests may be affected by danazol.

Danazol may rarely cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness, or other discoloration of the skin, or a severe sunburn. Check with your doctor if this occurs.

Do not take other medicines unless they have been discussed with your doctor.

SIDE EFFECTS

Androgen like effects include weight gain, acne and seborrhea. Mild hirsutism, edema, hair loss, voice change, which may take the form of hoarseness, sore throat or of instability or deepening of pitch, may occur and may persist after cessation of therapy. Hypertrophy of the clitoris is rare.

Other possible endocrine effects include menstrual disturbances in the form of spotting, alteration of the timing of the cycle and amenorrhea. Although cyclical bleeding and ovulation usually return within 60-90 days after discontinuation of therapy with Danazol, persistent amenorrhea has occasionally been reported.

Flushing, sweating, vaginal dryness and irritation and reduction in breast size, may reflect lowering of estrogen. Nervousness and emotional lability have been reported. In the male a modest reduction in spermatogenesis may be evident during treatment. Abnormalities in semen volume, viscosity, sperm count, and motility may occur in patients receiving long-term therapy.

Hepatic dysfunction, as evidenced by reversible elevated serum enzymes and/or jaundice, has been reported in patients receiving a daily dosage of Danazol of 400 mg or more. It is recommended that patients receiving Danazol be monitored for hepatic dysfunction by laboratory tests and clinical observation. Serious hepatic toxicity including cholestatic jaundice, peliosis hepatis, and hepatic adenoma have been reported.

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Purchasing medications online is quite risky, as you are in charge of the safety and effectiveness of the therapy, to some extent. At the same time, everything remains simple and clear – following the recommendations and safety instructions is the key to a flawless and successful course. However, be aware of the following side effects that may appear if you misuse the drug:

Rare

  • Bleeding gums
  • bloating, pain, or tenderness of the abdomen or stomach
  • blood in the urine
  • burning, numbness, pain, or tingling in all fingers except the smallest finger
  • changes in vision
  • chest pain
  • chills
  • complete or partial numbness or weakness on one side of body
  • cough
  • coughing up blood
  • diarrhea
  • difficulty with speaking
  • difficulty with swallowing
  • discharge from the nipple
  • eye pain
  • fast heartbeat
  • fever
  • headache
  • hives or other skin rash
  • joint pain
  • light-colored stools
  • loss of appetite (continuing)
  • loss of muscle coordination
  • more frequent nosebleeds
  • muscle aches
  • nausea
  • purple- or red-colored, or other spots on the body or inside the mouth or nose
  • restlessness
  • shortness of breath
  • sore throat
  • sweating
  • tingling, numbness, or weakness in the legs, which may move upward to the arms, trunk, or face
  • unusual bruising or bleeding
  • unusual tiredness, weakness, or general feeling of illness
  • vomiting
  • yellow eyes or skin
  • Enlarged clitoris
  • hoarseness or deepening of voice
  • unnatural hair growth
  • Changes in semen
  • decrease in the size of the testicles
  • Increased sensitivity of the skin to sunlight

More Common

  • Decrease in the breast size
  • irregular menstrual periods
  • weight gain

Less Common

  • Acne
  • dark-colored urine
  • increased oiliness of the hair or skin
  • muscle cramps or spasms
  • rapid weight gain
  • swelling of the feet or lower legs
  • unusual tiredness or weakness
  • Flushing or redness of the skin
  • mood or mental changes
  • nervousness
  • Burning, dryness, or itching of the vagina
  • vaginal bleeding
Type Small Molecule
Accession Number DB01406
Groups Approved
Synonyms
  • Cyclomen
  • Danazolum
UNII N29QWW3BUO
CAS number 17230-88-5
Weight Average: 337.4553
Monoisotopic: 337.204179113
Chemical Formula C22H27NO2
InChI
InChI=1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16-,17+,18+,20+,21+,22+/m1/s1
IUPAC Name
(1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.0²,¹⁰.0⁴,⁸.0¹⁴,¹⁸]icosa-4(8),5,9-trien-17-ol
Protein binding Not Available
Toxicity Not Available
Half life

Approximately 24 hours.

We are always expanding our borders, offering customers only the best services and the most convenient options. Currently, we are proud of international delivery, which is both fast and quality. The shipping time will not exceed 14 days, but can be considerably shorter, which depends mainly on the destination. Here is a list of Indian cities we ship medications to:

  • Mumbai
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