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Cialis

  • $0.68
  • Availability: In Stock
  • Active Ingredient Tadalafil
Cialis improves erection and helps to achieve a successful sexual intercourse.
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Apcalis   Adcirca   Afilta   Andrax   Apicalis  
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20 mg
Product name Per Pill Per Pack  
10 pills $3.54 $35.38
20 pills $2.39 $70.76 $47.83
30 pills $2.01 $106.13 $60.29
60 pills $1.63 $212.27 $97.64
90 pills $1.50 $318.40 $135.00
120 pills $1.44 $424.54 $172.36
180 pills $1.37 $636.80 $247.09
270 pills $1.33 $955.21 $359.15
360 pills $1.31 $1,273.61 $471.24
10 mg
Product name Per Pill Per Pack  
10 pills $3.51 $35.11
20 pills $2.28 $70.22 $45.67
30 pills $1.87 $105.34 $56.22
60 pills $1.46 $210.67 $87.88
90 pills $1.33 $316.01 $119.54
120 pills $1.26 $421.34 $151.20
180 pills $1.19 $632.02 $214.52
270 pills $1.15 $948.02 $309.50
360 pills $1.12 $1,264.03 $404.50
5 mg
Product name Per Pill Per Pack  
10 pills $3.38 $33.82
20 pills $2.09 $67.64 $41.90
30 pills $1.67 $101.46 $49.98
60 pills $1.24 $202.92 $74.21
90 pills $1.09 $304.38 $98.44
120 pills $1.02 $405.84 $122.68
180 pills $0.95 $608.76 $171.14
270 pills $0.90 $913.14 $243.86
360 pills $0.88 $1,217.52 $316.55
2.5 mg
Product name Per Pill Per Pack  
30 pills $1.38 $41.50
60 pills $1.00 $82.99 $60.13
90 pills $0.88 $124.49 $78.77
120 pills $0.81 $165.98 $97.40
180 pills $0.75 $248.98 $134.68
270 pills $0.71 $373.46 $190.59
360 pills $0.68 $497.95 $246.49

What is Cialis (tadalafil)?

Cialis (tadalafil) relaxes muscles and increases blood flow to particular areas of the body.
Cialis (tadalafil) is used to treat erectile dysfunction (impotence).
Cialis (tadalafil) may also be used for purposes other than those listed in this medication guide.

What should I discuss with my doctor before taking Cialis (tadalafil)?

Do not take Cialis (tadalafil) if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, and others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket). Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking tadalafil with a nitrate medicine can cause a serious decrease in blood pressure, leading to fainting, stroke, or heart attack.

A small number of patients have had a sudden loss of eyesight after taking tadalafil. This type of vision loss is caused by decreased blood flow to the optic nerve of the eye. It is not clear whether tadalafil is the actual cause of such vision loss. Sudden vision loss with tadalafil use has occurred most often in people with heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoke or are over 50 years old.

Before taking Cialis (tadalafil), tell your doctor if you have:
heart disease or heart rhythm problems;
a recent history of heart attack (within the past 90 days);
a recent history of stroke or congestive heart failure (within the past 6 months);
angina (chest pain);
high or low blood pressure;
liver disease;
kidney disease (or if you are on dialysis);
a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
a bleeding disorder such as hemophilia;
a stomach ulcer;
retinitis pigmentosa (an inherited condition of the eye);
a physical deformity of the penis (such as Peyronie's disease); or
if you have been told you should not have sexual intercourse for health reasons.

If you have any of these conditions, you may not be able to use tadalafil or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category B: Although tadalafil is not for use in women, this medication is not expected to be harmful to an unborn baby. Do not use tadalafil without telling your doctor if you are pregnant or plan to become pregnant during treatment.
Although Cialis (tadalafil) is not for use in women, it is not known if tadalafil passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
You may need a lower dose of this medication if you are older than 65. Follow your doctor's instructions.

How should I take Cialis (tadalafil)?

Take each dose with a full glass of water.
Avoid taking High-fat food before taking Cialis as it may cause the medicine to take more time to start working.
Tadalafil is usually taken only when needed, 30 - 60 minutes before sexual activity. The medication can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill.
Do not take tadalafil more than once a day. Allow 24 hours to pass between doses.
Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Since tadalafil is used as needed, you are not likely to be on a dosing schedule.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.
Symptoms of a tadalafil overdose may include chest pain, nausea, irregular heartbeat, and feeling light-headed or fainting.

What should I avoid while taking tadalafil?

Avoid drinking alcohol, which can increase some of the side effects of tadalafil.
Grapefruit and grapefruit juice may interact with tadalafil. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Do not use any other drug to treat impotence, such as alprostadil (Caverject, Muse, Edex) or yohimbine (Yocon, Yodoxin, others), unless your doctor tells you to.

What are the possible side effects of tadalafil?

If you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw during sexual activity, stop and call your doctor right away. You could be having a serious side effect of tadalafil.
Stop using tadalafil and get emergency medical help if you have sudden vision loss.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using tadalafil and call your doctor at once if you have any of these serious side effects:
chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
irregular heartbeat;
swelling in your hands, ankles, or feet;
shortness of breath;
vision changes;
feeling light-headed, fainting; or
penis erection that is painful or lasts 4 hours or longer.
Continue taking tadalafil and talk with your doctor if you have any of these less serious side effects:
warmth or redness in your face, neck, or chest;
stuffy nose;
headache;
upset stomach; or
back pain.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


What drug(s) may interact with Cialis (tadalafil)?

Do not take tadalafil if you are taking the following medications:
nitroglycerin-type drugs for the heart or chest pain such as amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin, even if these are only taken occasionally

Cialis (tadalafil) may also interact with the following medications:
alpha blockers, such as alfuzosin (UroXatral), doxazosin (Cardura), prazosin (Minipress), or terazosin (Hytrin), used to treat high blood pressure or an enlarged prostate.
bosentan
certain antibiotics such as clarithromycin, erythromycin, troleandomycin
certain drugs used for seizures such as carbamazepine, phenytoin, and phenobarbital
cimetidine
cisapride
diltiazem
grapefruit juice
medicines for fungal infections (fluconazole, itraconazole, ketoconazole, voriconazole)
mibefradil
nicardipine
certain medicines for the treatment of HIV infection or AIDS
quinidine
rifabutin, rifampin or rifapentine
some drugs for treating depression, anxiety or other mood problems (examples: fluoxetine, fluvoxamine, nefazodone)
verapamil

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Purchasing medications online is quite risky, as you are in charge of the safety and effectiveness of the therapy, to some extent. At the same time, everything remains simple and clear – following the recommendations and safety instructions is the key to a flawless and successful course. However, be aware of the following side effects that may appear if you misuse the drug:

Rare

  • Painful or prolonged erection of the penis
  • Changes in color vision

More Common

  • Acid or sour stomach
  • belching
  • heartburn
  • indigestion
  • stomach discomfort, upset, or pain

Less Common

  • Arm, back, or jaw pain
  • blurred vision
  • chest pain or discomfort
  • chest tightness or heaviness
  • chills
  • cold sweats
  • confusion
  • dizziness
  • fainting
  • faintness or lightheadedness when getting up suddenly from a lying or sitting position
  • fast or irregular heartbeat
  • headache
  • hearing loss
  • nausea
  • nervousness
  • pain or discomfort in the arms, jaw, back, or neck
  • pounding in the ears
  • shortness of breath
  • slow or fast heartbeat
  • sweating
  • unusual tiredness or weakness
  • vomiting
  • Bloody nose
  • body aches or pain
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • burning, dry, or itching eyes
  • burning feeling in the chest or stomach
  • congestion
  • difficulty with moving
  • difficulty with swallowing
  • dry mouth
  • dryness or soreness of the throat
  • excessive eye discharge
  • eye pain
  • feeling of constant movement of self or surroundings
  • feeling of warmth, redness of the face, neck, arms and occasionally, upper chest
  • fever
  • hoarseness
  • increased erection
  • lack or loss of strength
  • loose stools
  • muscle aching or cramping
  • muscle stiffness
  • nasal congestion
  • neck pain
  • pain
  • pain in the arms or legs
  • pain or burning in the throat
  • redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
  • reduced sensitivity to touch
  • runny nose
  • sensation of spinning
  • sleepiness or unusual drowsiness
  • sleeplessness
  • spontaneous penile erection
  • stomach upset
  • swelling of the eyelids
  • swelling or puffiness of the eyes or face
  • swollen joints
  • tearing
  • tender, swollen glands in the neck
  • tenderness in the stomach area
  • trouble with sleeping
  • unable to sleep
  • upper abdominal or stomach pain
  • voice changes
  • watering of the eyes

Incidence Not Known

  • Abdominal or stomach pain
  • blindness
  • blistering, peeling, or loosening of the skin
  • cough
  • cracks in the skin
  • decrease or change in vision
  • diarrhea
  • difficulty with speaking
  • double vision
  • fast, irregular, pounding, or racing heartbeat or pulse
  • headache, severe and throbbing
  • hives or welts
  • inability to move the arms, legs, or facial muscles
  • inability to speak
  • itching
  • joint or muscle pain
  • loss of heat from the body
  • numbness or tingling of the face, hands, or feet
  • red irritated eyes
  • red skin lesions, often with a purple center
  • red, swollen skin
  • redness of the skin
  • redness or soreness of the eyes
  • scaly skin
  • skin rash
  • slow speech
  • sores, ulcers, or white spots in the mouth or on the lips
  • sudden cardiac death
  • swelling of the feet or lower legs
Type Small Molecule
Accession Number DB00820  (APRD00071)
Groups Approved, Investigational
Synonyms
  • (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
  • (6R,12AR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
  • 6-BENZO[1,3]dioxol-5-yl-2-methyl-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
  • ICOS 351
  • Tadanafil
UNII 742SXX0ICT
CAS number 171596-29-5
Weight Average: 389.404
Monoisotopic: 389.137556111
Chemical Formula C22H19N3O4
InChI
InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1
IUPAC Name
(2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0³,⁸.0¹¹,¹⁶]heptadeca-1(10),11,13,15-tetraene-4,7-dione
Protein binding

94%

Toxicity

Oral, Rat LD50 = 2000 mg/kg, no deaths or toxicity.

Half life

17.5 hours

We are always expanding our borders, offering customers only the best services and the most convenient options. Currently, we are proud of international delivery, which is both fast and quality. The shipping time will not exceed 14 days, but can be considerably shorter, which depends mainly on the destination. Here is a list of Indian cities we ship medications to:

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  • Maheshtala