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Nizoral

  • $1.15
  • Availability: In Stock
  • Active Ingredient ketoconazole
Nizoral is an antifungal antibiotic used to treat candidiasis, blastomycosis, coccidioidomycosis, histoplasmosis, chromoblastomycosis, or paracoccidioidomycosis.
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200 mg
Product name Per Pill Per Pack  
30 pills $2.01 $60.28
60 pills $1.54 $120.56 $92.28
90 pills $1.38 $180.84 $124.28
120 pills $1.30 $241.12 $156.29
180 pills $1.22 $361.67 $220.28
270 pills $1.17 $542.51 $316.31
360 pills $1.15 $723.35 $412.31

Product Description

Common use

Nizoral is an antifungal antibiotic used to treat serious fungal or yeast infections, such as candidiasis, blastomycosis, coccidioidomycosis, histoplasmosis, chromoblastomycosis, or paracoccidioidomycosis. Nizoral kills sensitive fungi by interfering with the formation of the fungal cell membrane. Also Nizoral is used to treat parasitic fungal infections on the skin that cannot be treated with topical medicine or griseofulvin, or for patients who cannot take griseofulvin.

Dosage and direction

Take it orally with food or milk at the same time each day.
The recommended starting dose for adults is 200 mg once a day.
Dosage for 2-year-old children is based on body weight. A single daily dose varies from  3.3 to 6.6 mg/kg . Do not use it without doctor's permission and dose has to be prescribed just after consulting your doctor.
For children under the age of 2, use it just after doctor's permission and dose has to be prescribed after consulting your doctor.
Note: this instruction presented here just for review. It's very necessary to consult your doctor before using.

Precautions

Liver problems may occur while you are taking this medicine. If you experience one of this symptoms as dark urine; abdominal pain or tenderness; clay-colored stools; nausea and vomiting; decreased appetite; skin rash; fever; headache; itching; loss of appetite; swelling of the feet or lower legs; unusual tiredness or weakness; or yellow eyes or skin call your doctor immediately . Nizoral should not be used during pregnancy, becoming pregnant or lactating without doctor's advice. Do not use this drug before breast-feeding without doctor's permission.

Contraindications

Nizoral is not allowed to people who are hypersensitive to any components of this medication. Also it is contraindicated with terfenadine, astemizole, triazolam, cisapride. 

Possible side effect

They may include an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Also the most possible side effects include:
dizziness, fainting, fast or pounding heartbeat;
easy bruising or bleeding, unusual weakness;
numbness or tingly feeling;
severe depression, confusion, or thoughts of hurting yourself; or
nausea, stomach pain, low fever, loss of appetite, weakness, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious include:
mild nausea, vomiting, or stomach pain;
mild itching or skin rash;
headache;
dizziness;
breast swelling; or
impotence or loss of interest in sex.
If you experience one of them stop using Nizoral and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction

Nizoral interact with follow list of drugs: acetaminophen (Tylenol); cyclosporine (Gengraf, Sandimmune, Neoral); digoxin (digitalis, Lanoxin); tacrolimus ((Prograf); loratadine (Alavert, Claritin, Tavist ND); methylprednisolone (Medrol); phenytoin (Dilantin); rifampin (Rifadin, Rifater, Rifamate, Rimactane); diabetes medication you take by mouth; a sedative such as midazolam (Versed); a blood thinner such as warfarin (Coumadin); cancer medications; birth control pills or hormone replacement therapy; methotrexate (Rheumatrex, Trexall); cholesterol medications such as niacin (Advicor), atorvastatin (Lipitor), lovastatin (Altocor, Mevacor), simvastatin (Zocor), and others; or medications to treat HIV or AIDS. Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usually dose next day in the same regularly time.

Overdose

Symptoms of Nizoral overdose are not known well, but if you experience any unusual symptoms call your doctor immediately. Also in the event of accidental over-dosage, supportive measures, including gastric lavage with sodium bicarbonate, should be employed.

Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Purchasing medications online is quite risky, as you are in charge of the safety and effectiveness of the therapy, to some extent. At the same time, everything remains simple and clear – following the recommendations and safety instructions is the key to a flawless and successful course. However, be aware of the following side effects that may appear if you misuse the drug:

Rare

  • Back, leg, or stomach pains
  • black, tarry stools
  • bleeding gums
  • blood in the urine or stools
  • blurred vision
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • change in color vision
  • change in the ability to see colors, especially blue or yellow
  • chest pain
  • chills
  • confusion
  • cough
  • dark urine
  • difficulty seeing at night
  • difficulty swallowing
  • dizziness
  • fast heartbeat
  • fever
  • general body swelling
  • headache
  • hoarseness
  • increased sensitivity of the eyes to sunlight
  • irritation
  • joint pain, stiffness, or swelling
  • light-colored stools
  • loss of appetite
  • mood or mental changes
  • nausea or vomiting, severe
  • nosebleeds
  • painful or difficult urination
  • pale skin
  • pinpoint red spots on the skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • skin rash, hives, itching
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swelling of the eyelids, face, lips, hands, or feet
  • swollen glands
  • tightness in the chest
  • trouble sleeping
  • troubled breathing or swallowing
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vision changes
  • yellow eyes or skin
  • Change in number of sperm and their ability to move
  • decreased interest in sexual intercourse
  • diarrhea
  • hair loss or thinning of the hair
  • inability to have or keep an erection
  • loss in sexual ability, desire, drive, or performance
  • sleepiness or unusual drowsiness
  • swelling of the breasts or breast soreness for both female and male
Type Small Molecule
Accession Number DB01026  (APRD00401)
Groups Approved, Investigational
Synonyms
  • Ketoconazol
  • Ketoconazole
  • Ketoconazolum
  • Ketozole
UNII R9400W927I
CAS number 65277-42-1
Weight Average: 531.431
Monoisotopic: 530.148760818
Chemical Formula C26H28Cl2N4O4
InChI
InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3
IUPAC Name
1-[4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethan-1-one
Protein binding

99% (in vitro, plasma protein binding)

Toxicity

Hepatotoxicity, LD50=86 mg/kg (orally in rat)

Half life

2 hours

We are always expanding our borders, offering customers only the best services and the most convenient options. Currently, we are proud of international delivery, which is both fast and quality. The shipping time will not exceed 14 days, but can be considerably shorter, which depends mainly on the destination. Here is a list of Indian cities we ship medications to:

  • Mumbai
  • Delhi
  • Bangalore
  • Hyderabad
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  • Pimpri & Chinchwad
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